Department of Musculoskeletal Oncology and Orthopaedic Surgery

About us

Target diseases

  • Malignant bone and soft tissue tumors (Sarcomas)
  • Benign bone and soft tissue tumors
  • Metastatic bone tumors
  • Orthopaedic diseases in cancer patients

Features of our department

Malignant tumors that develop in the internal organs are called cancers, whereas malignant tumors that arise from bones and soft tissue organs are called sarcomas or malignant bone and soft tissue tumors. Sarcoma is one of the rare cancers that occurs in a small number of cases and must be treated at a hospital with a specialist. In our department, a sarcoma specialist consisting of two full-time physicians and three part-time physicians will provide appropriate treatment for sarcomas while snuggling up to patients.

Sarcoma treatment can be broadly divided into three categories: surgery, radiotherapy, and chemotherapy. Some of these treatments are difficult to perform in our department. Therefore, if special treatment is necessary, it is also possible to make the most of our network to refer you to those hospitals including National Cancer Center, Keio University Hospital, Saitama Cancer Center, etc.

clinical or basic research, and research efforts aimed at developing new treatments for sarcoma
Unfortunately, sarcoma is a rare cancer, and the research base for new diagnostic and treatment methods is not well established. As a result, treatments for sarcoma have not advanced for nearly 30 years. Therefore, our department actively participates not only in Japan but also in academic societies abroad, and actively provides information to patients who have no treatment and who are in need of helping to open the way. In addition, in collaboration with National Cancer Center Research Institute and Keio University Hospital, we will conduct clinical and basic research aimed at developing new diagnostic and therapeutic methods.

Depending on the type of cancer, the dramatic progress in therapies in recent years has led to an era in which long-term survival can be expected in cancer patients with bone metastases. Patients with bone metastases may experience long-term survival, but their quality of life may be reduced due to symptoms such as pain, fractures and spinal cord paralysis and they may not be able to live as expected. Therefore, in cooperation with the Department of Rehabilitation, our department will perform management aimed at improving the quality of life of patients with bone metastases.

In addition to the symptoms of cancer, cancer patients may also experience symptoms such as low back pain, knee pain, and numbness in legs due to problems with common orthopedic diseases. In our department, we will also actively work on general orthopedic disease problems for cancer-bearing patients. For general orthopedic problems, the specialized facilities may be able to receive more complete treatment, so we will also refer you to specialized facilities as needed.

Clinical research conducted in our department

  1. Immunohistochemical study of the usefulness of DCBLD2 as invasiveness biomarker for myxofibrosarcoma
  2. Multi-institutional joint research for understanding the molecular pathology of bone and soft tissue tumors based on genome-proteome analysis and its clinical application
  3. Examination of usefulness of cancer gene test in Japanese patients with soft tissue sarcoma
  4. Elucidation of pathology of bone and soft tissue tumors by genome and epigenome analysis
  5. A study to evaluate the usefulness of tumor invasion area evaluation and differential diagnosis using sonazoid contrast-enhanced echo for soft tissue tumors
  6. Study on construction of the Japanese Orthopedic Association Case Registry (JOANR)
  7. Clinicopathological study of giant cell tumors
  8. A retrospective study on the therapeutic effect of decompression with a hollow screw on pediatric simple bone cysts
  9. Multicenter study on treatment outcome of dedifferentiation case of low grade osteosarcoma
  10. Treatment outcome of primary high-grade malignant bone tumor in middle-aged and elderly Research -Japanese Musculosekeltal Oncology Group (JMOG) multicenter research-
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